Chiral Column

Chiral column is an important part of chiral isolation which is the most environment-friendly method to separate chiral chemicals in the world.  Using Supercritical Fluid Chromatography (SFC) with CO2, there are no toxic separate media involved or discharged during the production. GALAK chiral column have many advantages.

  • Reduce medicine production cost, No emissions of toxic substances
  • High purification of the target substance
  • Widely applied for different chiral chemicals
  • Long life-time, Renewable
liquid chromatography column

Polysaccharide-derived Normal Phase Chiral Column

Cellulose tris (3,5 – dimethyl phenyl carbamyl) coated on silica support

  1. High enantiomeric purity: e.e. ≥99%, Yield ≥ 85%
  2. Quantities produced ranges: milligrams – kilograms
  3. Suitable for Supercritical Fluid Chromatography (SFC) equipment
  4. Chiral separation services are available

Particle Size: 3 – 5 μm

Application Of Chiral Column

Sitafloxacin Hydrate

  • Flowing Phase: Hex(0.1%TFA)/IPA=90/10
  • Flow Velocity: 1 ml/min
  • Pressure: 4.0MPa
  • Solvent: Hexane
chiral seperation

Duloxetine HCl

  • Flowing Phase: Hex(0.1%TFA)/IPA=90/10
  • Flow Velocity: 1 ml/min
  • Pressure: 5.3MPa
  • Dissolve in MeOH, dilute with flowing phase
chiral seperation

Notice:

  1. Strictly operate according to the chiral technical manual.
  2. Do not use the following chemicals as flowing phases or solvents, they cost irreversible destruction for chiral media: DMF, DMSO, Dioxane, Toluene, THF, Chloroform, Dichloromethane, Acetone, Ethyl acetate.
  3. Contact us immediately, when there is any question during operation.

More details, contact us >>

Need help with easier liquid chromatography solutions? We are experts!