Low-Pressure Liquid Chromatography System

GALAK Chromatography Technology provides low-pressure liquid chromatography (LPLC) system includes LPLC columns, the control system, liquid mixer, which is widely used in pharmaceutical areas.

  • Patented products, high cost-effective, OEM is available
  • Corollary equipment, technical support
  • Multiple choices for packing materials
GALAK LPLC system
GALAK Chromatography auto column system
GALAK Chromatography auto column system

Low-pressure Chromatography Columns

Manual Packing Column

  1. Cover all diameter
    • Customization is available
  2. Patent column head sealing technology
    • Lever-pressing sealing structure was used with high reliability, which prevents the problem that the pneumatic mechanism easy to leak and invalid
    • The expansion structure of pressurizing-down style gasket ring prevents column head departing from bed caused by the pull-up structure
    • Minimized Hold-up Volumes, Easy to clean and change the seal
  3. Patent column head rotating structure
    • Column head rotate by the rotating screw of the column pipe, which is in the upper surface of Flange plate After rotating in place, the second screw need to be inserted. Media packing can be done after rotating column head. It is easy to operate, without carrying out the column head
  4. Predictable linear scale up
    • Fix condition:Linear flow rate, buffer, packing material, bed height, sample concentration and pH, sapmle volume and bed volume ratio
    • Scale up condition: Column I.D., volume flow rate, sample volume
low-pressure ghromatography column
low pressure liquid chromatography glass column tube
low pressure liquid chromatography glass column bottom
low pressure liquid chromatography glass column head

Column Parameters:

Column 100Column 140Column 200Column 300Column 450

Column Size

100*500mm140*500mm200*500mm300*500mm

450*500mm

Tubing Inner-diameter

4mm4mm6mm6mm

10mm

Column Bed Height

50-300mm

Tube Material

Schott Glass / 316L Stainless Steel

Wet-part Material

316L Stainless Steel / PP / PEEK / EPDM

Pressure

Glass6 bar5 bar5 bar5 bar

5 bar

316L SS

7 bar7 bar7 bar5 bar

5 bar

Ingress Protection

IP65

Temperature

4-40℃

* OEM service for glass column tube is available.

Automatic Packing Column

  1. Intelligent Packing process
    • Pump, Valves, Touch Screen and Framework
    • All operations could be done on Touch Screen
    • Using wizard to maintain, pack and unpack the column, avoiding mistakes
    • Endpoint of packing is determined by sensors, and repeatability is excellent
  2. Simple
    • Packing Station use pneumatic diaphragm valves to control every flow path independently, and easy to clean
  3. Patented Distributor
    • Using fluid dynamics simulation to predict distributor performance
    • The maximal column is 1200mm
    • Customization is available
  4. Patented Tube Rotation Structure
    • Special structure, easy operation and reliable
    • Loosen screws on the bottom of the column, the tube can be lifted up and rotated avoiding damage from misoperation
automatic-packing-liquid-chromatography-glass-column-4
automatic column
automatic-packing-liquid-chromatography-glass-column-1

Column Parameters:

 

Column 450Column 600Column 800Column 1000
Column Size450*550mm630*550mm800*550mm

1000*550mm

Thickness Of Column Tube Wall

20mm30mm40mm51mm
Column Bed Height

50-350mm

Tube Material

Acrylic / 316L Stainless Steel
Wet Part Material

316L Stainless Steel / PP / PEEK / EPDM

Max Pressure

5 Bar

Ingress Protection

IP56

Temperature

4-40℃

* OEM service for glass column tube is available.

Semi-automatic Packing System

The column height of the semi-automatic column bed is set by the rotation of the screw on the upper part of the column tube. The column station is adopted to install the column by the upper and lower nozzle assembly. The upper and lower nozzles are pneumatic nozzles. The opening and closing of nozzles can be controlled by the post workstation, so as to realize loading and unloading of packing materials.

  • Bed height can be set and adjusted
  • The column-loading environment is closed, safe and reliable
  • With upper and lower automatic sprinkler head, easy to load and unload
  • Small structure, small footprint
semi-automatic-liquid-chromatography-glass-column

Column Parameters:

 

Column 450Column 600Column 800Column 1000
Column Size450*550mm630*550mm800*550mm

1000*550mm

Column Bed Height

50-350mm
Tube Material

Acrylic / 316L Stainless Steel

Wet Part Material

316L Stainless Steel / PP / PEEK / EPDM
Max Pressure

5 Bar

Ingress Protection

IP56
Temperature

4-40℃

* OEM service for glass column tube is available.

Low-pressure Chromatography System

Smart Liquid Preparation System

Advantages:

  • Real-time data acquisition, System Log; UPS optional to protect data from unexpected power failure; Compare different batch curves
  • Customer naming in/out let
  • Complete user permission management, FDA 21 CFR part 11 compliant
  • Powerful method editor, scouting best method
  • Software upgrade service
  • Gradient Editor, easy to set volume and conductivity gradient, linear or step
  • Result report can be made by using Wizard
  • Powerful chromatography process function, easy to get analysis of the product
GALAK Chromatography auto prep system

AutoPilot Chromatography System

Advantages:

  1. Apply for pilot process development and sample
    • Max flow rate is 1L/min with single pump
    • Co-ordinate with lab column or Easy Column 100 or 140
  2. Customer design for multiple configuration
    • USP Class VI compatible material, SS shell, IP 65 protection level
    • FAT, DQ/Q/OQ validation file system
  3. Main Parts of the system
    • Piston pump: PEEK/316L pump head, with chemical resistance, and high accuracy
    • Electronic diaphragm valve: Minimum hold-up volume and modular design
    • Pressure sensor: High accuracy for protecting column and system
    • pH/Conductivity: temperature compensation and online calibration
GALAK LPLC autopilot system

AutoPrep Industrial  Chromatography System

Advantages:

  1. Customization
  2. Compact structure, stacked pipeline, minimum dead volume
  3. Real-time monitoring valve feedback design
    • Each valve is installed with valve feedback, real-time monitoring valve open (closed) state, to ensure the normal operation of the production.
  4. Humanized and aesthetically pleasing electrical components and circuit layout
    Easy to operate and maintain
  5. Independent development of control software
    • In line with FDA specifications, data and logs are recorded in real time, traceable and unmodifiable.
  6. Simple and intuitive software operation interface
  7. Menu function Settings, more orderly operation, easier to grasp quickly
  8. Flexible and powerful method editing function
    • Based on the time, volume, column volume automatic process production.
  9. Stable and reliable data acquisition and management functions
    • Real-time record saving, no loss of power failure data;
  10. The materials of the comply with USP Class Ⅵ can ne tracked
  11. Comply with other requirements in URS and complete VERIFICATION of FAT and DQ/IQ documents
industrial-chromatography-system
auto-pilot low-pressure liquid chromatography system
auto-pilot low-pressure liquid chromatography system
auto-pilot low-pressure liquid chromatography system
auto-pilot low-pressure liquid chromatography system

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