Low-Pressure Liquid Chromatography System

GALAK Chromatography Technology provides low-pressure liquid chromatography (LPLC) system includes LPLC columns, the control system, liquid mixer, which is widely used in pharmaceutical areas.

  • Patented products, high cost-effective, OEM is available
  • Corollary equipment, technical support
  • Multiple choices for packing materials
GALAK LPLC system
GALAK Chromatography auto column system
GALAK Chromatography auto column system

Chromatography Columns

Manual Column

  1. Cover all diameter
    • Customization is available
  2. Patent column head sealing technology
    • Lever-pressing sealing structure was used with high reliability, which prevents the problem that the pneumatic mechanism easy to leak and invalid
    • The expansion structure of pressurizing-down style gasket ring prevents column head departing from bed caused by the pull-up structure
    • Minimized Hold-up Volumes, Easy to clean and change the seal
  3. Patent column head rotating structure
    • Column head rotate by the rotating screw of the column pipe, which is in the upper surface of Flange plate After rotating in place, the second screw need to be inserted. Media packing can be done after rotating column head. It is easy to operate, without carrying out the column head
  4. Predictable linear scale up
    • Fix condition:Linear flow rate, buffer, packing material, bed height, sample concentration and pH, sapmle volume and bed volume ratio
    • Scale up condition: Column I.D., volume flow rate, sample volume
low pressure liquid chromatography column
low pressure liquid chromatography column

Column Parameters:

 

Column 50

Column 100Column 140Column 200Column 300

Column 450

Tube Material

Acrylic / Glass / 316L Stainless Steel

Wet part Material

316L Stainless Steel / PP / PEEK / EPDM

Max Pressure

Glass

6 bar

5 bar5 bar5 bar3 bar

--

Acrylic

6 bar

5 bar5 bar5 bar5 bar5 bar
316L SS7 bar7 bar7 bar7 bar5 bar

5 bar

Ingress Protection

IP65

Temperature

4-40℃

Gross Weight

12kg

20kg38kg50kg100kg

220kg

Automatic Column

  1. Intelligent Packing process
    • Pump, Valves, Touch Screen and Framework
    • All operations could be done on Touch Screen
    • Using wizard to maintain, pack and unpack the column, avoiding mistakes
    • Endpoint of packing is determined by sensors, and repeatability is excellent
  2. Simple
    • Packing Station use pneumatic diaphragm valves to control every flow path independently, and easy to clean
  3. Patented Distributor
    • Using fluid dynamics simulation to predict distributor performance
    • The maximal column is 1200mm
    • Customization is available
  4. Patented Tube Rotation Structure
    • Special structure, easy operation and reliable
    • Loosen screws on the bottom of the column, the tube can be lifted up and rotated avoiding damage from misoperation
Low pressure liquid chromatography column
automatic column

Column Parameters:

 

Column 300Column 450Column 600Column 800Column 1000Column 1200Column 1600

Tube Material

Acrylic / 316L Stainless Steel

Wet part Material

316L Stainless Steel / PP / PEEK / EPDM

Max Pressure

3/5 bar

Ingress Protection

IP65
Temperature

4-40℃

Gross Weight300kg650kg900kg1400kg2000kg2500kg

3500kg

Corollary Equipment

Smart Chromatography System

Advantages:

  • Real-time data acquisition, System Log; UPS optional to protect data from unexpected power failure; Compare different batch curves
  • Customer naming in/out let
  • Complete user permission management, FDA 21 CFR part 11 compliant
  • Powerful method editor, scouting best method
  • Software upgrade service
  • Gradient Editor, easy to set volume and conductivity gradient, linear or step
  • Result report can be made by using Wizard
  • Powerful chromatography process function, easy to get analysis of the product
GALAK Chromatography auto prep system

AutoPilot System

Advantages:

  1. Apply for pilot process development and sample
    • Max flow rate is 1L/min with single pump
    • Co-ordinate with lab column or Easy Column 100 or 140
  2. Customer design for multiple configuration
    • USP Class VI compatible material, SS shell, IP 65 protection level
    • FAT, DQ/Q/OQ validation file system
  3. Main Parts of the system
    • Piston pump: PEEK/316L pump head, with chemical resistance, and high accuracy
    • Electronic diaphragm valve: Minimum hold-up volume and modular design
    • Pressure sensor: High accuracy for protecting column and system
    • pH/Conductivity: temperature compensation and online calibration
GALAK LPLC autopilot system

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